TargetMol

Ibutilide Fumarate

Product Code:
 
TAR-T6541
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6541-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T6541-10mg10mg£111.00
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TAR-T6541-25mg25mg£136.00
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TAR-T6541-50mg50mg£148.00
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TAR-T6541-100mg100mg£214.00
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TAR-T6541-200mg200mg£287.00
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This product comes from: United States.
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Further Information

Bioactivity:
Ibutilide Fumarate is the fumarate salt form of ibutilide, a class III antiarrhythmic agent. Ibutilide exerts its effect by activating a slow, inward, predominately sodium current rather than by blocking outward potassium currents. This results in prolongation of atrial and ventricular action potential duration and refractory periods. Ibutilide slightly decreases the sinus rate and atrioventricular (AV) conduction and produces a dose-related prolongation of the QT interval.
CAS:
122647-32-9
Formula:
C44H76N4O10S2
Molecular Weight:
885.23
Pathway:
Membrane transporter/Ion channel; Metabolism
Purity:
0.9968
SMILES:
OC(=O)C=CC(O)=O.CCCCCCCN(CC)CCCC(O)c1ccc(NS(C)(=O)=O)cc1.CCCCCCCN(CC)CCCC(O)c1ccc(NS(C)(=O)=O)cc1
Target:
Calcium Channel; Sodium Channel

References

Davies M R, Martinec M, Walls R, et al. Use of Patient Health Records to Quantify Drug-Related Pro-arrhythmic Risk[J]. Cell Reports Medicine. 2020, 1(5): 100076. Ruan L, Quan X, Li L, Bai R, Ni M, Xu R, Zhang C.Exp Ther Med. 2014 May;7(5):1279-1284. Epub 2014 Mar 4. Simon A, et al.Europace. 2016 Mar 22.