TargetMol

Tazarotene

Product Code:
 
TAR-T6696
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6696-10mg10mg£107.00
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Quantity:
TAR-T6696-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T6696-25mg25mg£136.00
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TAR-T6696-50mg50mg£191.00
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Quantity:
TAR-T6696-100mg100mg£287.00
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Quantity:
TAR-T6696-200mg200mg£352.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
Tazarotene is a synthetic, topical retinoid. Tazarotene induces the expression of tazarotene-induced gene 3 (TIG3), a tumor suppressor gene. In psoriasis, tazarotene normalizes abnormal keratinocyte differentiation and reduces their hyperproliferation.
CAS:
118292-40-3
Formula:
C21H21NO2S
Molecular Weight:
351.46
Pathway:
Metabolism; Autophagy
Purity:
0.9967
SMILES:
CCOC(=O)c1ccc(nc1)C#Cc1ccc2SCCC(C)(C)c2c1
Target:
Retinoid Receptor; Autophagy

References

Duvic M, et al. J Am Acad Dermatol, 1997, 37(2 Pt 3), S18-24. So PL, et al. Cancer Res, 2004, 64(13), 4385-4389. Yen A, et al. Mol Pharmacol, 2004, 66(6), 1727-1737. Zeng X, Zhu S, Lu W, et al. Target identification among known drugs by deep learning from heterogeneous networks[J]. Chemical Science. 2020, 11(7): 1775-1797. Zeng X, Zhu S, Lu W, et al. Target identification among known drugs by deep learning from heterogeneous networks. Chemical Science. 2020, 11(7): 1775-1797. Duvic M, et al. Expert Opin Investig Drugs, 1997, 6(10), 1537-1551. Ogawa A, et al. Jpn J Pharmacol, 1998, 76(3), 317-319.