TargetMol

FCCP

Product Code:
 
TAR-T6834
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6834-5mg5mg£99.00
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Quantity:
TAR-T6834-1mL1 mL * 10 mM (in DMSO)£111.00
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Quantity:
TAR-T6834-10mg10mg£111.00
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Quantity:
TAR-T6834-25mg25mg£144.00
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Quantity:
TAR-T6834-50mg50mg£204.00
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Quantity:
TAR-T6834-100mg100mg£319.00
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Quantity:
TAR-T6834-200mg200mg£487.00
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Quantity:
TAR-T6834-500mg500mg£736.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
FCCP, a potent uncoupler of oxidative phosphorylation in mitochondria, transport protons across cell membranes leading to disrupts ATP synthesis.
CAS:
370-86-5
Formula:
C10H5F3N4O
Molecular Weight:
254.172
Pathway:
Metabolism; Membrane transporter/Ion channel
Purity:
0.995
SMILES:
FC(F)(F)Oc1ccc(NN=C(C#N)C#N)cc1
Target:
ATPase; Mitochondrial Metabolism

References

Mu?oz F, et al. FEBS Lett. 2001, 492(1-2):156-159. Shi J, Zhang F, Chen L, et al. Systemic mitochondrial disruption is a key event in the toxicity of bacterial pore?forming toxins to Caenorhabditis elegans. Environmental Microbiology. 2021 Sep;23(9):4896-4907 Liang S, Zhu C, Suo C, et al. Mitochondrion-Localized SND1 Promotes Mitophagy and Liver Cancer Progression Through PGAM5. Frontiers in Oncology. 2022, 12: 857968-857968 Guimar?es EL, et al. BMC Gastroenterol. 2012, 12:68. Liu H, Sun Y, Xu H, et al. PTEN-induced putative kinase 1 regulates mitochondrial quality control and is essential for the maturation of human induced pluripotent stem cell-derived cardiomyocytes. Genes & Diseases. 2022 Shi J, Zhang F, Chen L, et al. Systemic mitochondrial disruption is a key event in the toxicity of bacterial pore?forming toxins to Caenorhabditis elegans[J]. Environmental Microbiology. Zander-Fox DL, et al. Biol Reprod. 2015, 92(5):124.