TargetMol

7-Acetoxy-4-methylcoumarin

Product Code:
 
TAR-T7037
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7037-5mg5mg£113.00
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TAR-T7037-1mL1 mL * 10 mM (in DMSO)£116.00
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TAR-T7037-10mg10mg£131.00
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TAR-T7037-25mg25mg£173.00
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TAR-T7037-50mg50mg£225.00
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TAR-T7037-100mg100mg£301.00
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TAR-T7037-200mg200mg£417.00
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Further Information

Bioactivity:
7-Acetoxy-4-methylcoumarin is a fluorogenic substrate for carboxylesterase yielding a blue fluorescent solution upon cleavage. The compound has been used in aprotic media, a cell membrane environmental mimic, to study superoxide and related oxyl-radical reactions of model biological membranes dispersed in aqueous media. Due to the ability for AchE to cleave and activate 7-Acetoxy-4-methylcoumarin, the fluorogenic substrate has been used to study the AchE inhibitor Tacrine?HCl (sc-200172). The compound has also been isolated from Trigonella foenum graceum.
CAS:
2747-05-9
Formula:
C12H10O4
Molecular Weight:
218.208
Purity:
0.8844
SMILES:
CC(=O)Oc1ccc2c(C)cc(=O)oc2c1

References

Frimer AA,et al. Can superoxide organic chemistry be observed within the liposomal bilayer? Free Radic Biol Med. 1996;20(6):843-52. Berman HA,et al.Interaction of tetrahydroaminoacridine with acetylcholinesterase and butyrylcholinesterase.Mol Pharmacol. 1992 Feb;41(2):412-8.