TargetMol

alpha-Tocopherolquinone

Product Code:
 
TAR-T7050
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7050-10mg10mg£95.00
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Quantity:
TAR-T7050-1mL1 mL * 10 mM (in DMSO)£98.00
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TAR-T7050-25mg25mg£122.00
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TAR-T7050-50mg50mg£145.00
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This product comes from: United States.
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Further Information

Bioactivity:
During hypoxia in rats, levels of α-tocopherylquinon have been found to rise. It is reported to downregulate the respiratory activity of mitochondria. It has also displayed antioxidant activities after it is reduced to tocopherylhydroquinone.
CAS:
7559-04-8
Formula:
C29H50O3
Molecular Weight:
446.716
Pathway:
oxidation-reduction
Purity:
0.9813
SMILES:
CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@@](C)(O)CCC1=C(C)C(=O)C(C)=C(C)C1=O
Target:
Antioxidant

References

Lars Gille, et al. Redox-interaction of ?-tocopheryl quinone with isolated mitochondrial cytochrome complex[J]. Biochemical Pharmacology, 2004, 68(2):373-381. Siegel D, et al. The Reduction of ?-Tocopherolquinone by Human NAD(P)H:Quinone Oxidoreductase: The Role of ?-Tocopherolhydroquinone as a Cellular Antioxidant[J]. Molecular Pharmacology, 1997, 52(2):300-305. Kanazawa H, et al. Determination of ?-tocopherol and ?-tocopherylquinone in rat tissues and plasma by high-performance liquid chromatography with electrochemical detection.[J]. Chemical & Pharmaceutical Bulletin, 2000, 48(10):1462-1466.