TargetMol

OXOMEMAZINE

Product Code:
 
TAR-T9353
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9353-10mg10mg£109.00
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Further Information

Bioactivity:
Oxomemazine is a phenothiazine-based histamine H1-receptor blocker with pronounced antimuscarinic activity. Oxomemazine is a selective antagonist of mycotoxins M1 receptors, showing high (Ki=84 nM, M1 receptors) and low (Ki=1.65 μM, M2 receptors) affinity sites 20 times the difference[1]. Oxomemazine is an antihistamine and anticholinergic agent used in studies related to cough studies[2].
CAS:
3689-50-7
Formula:
C18H22N2O2S
Molecular Weight:
330.44
Pathway:
Neuroscience; Immunology/Inflammation; GPCR/G Protein
Purity:
0.9949
SMILES:
CC(CN(C)C)CN(c1c2cccc1)c(cccc1)c1S2(=O)=O
Target:
AChR; Histamine Receptor

References

S W Lee, et al.Selectivity of oxomemazine for the M1 muscarinic receptors.Arch Pharm Res. 1994 Dec;17(6):443-51. M S Siddegowda, et al.Oxomemazine hydro-chloride. Acta Crystallogr Sect E Struct Rep Online. 2011 Aug 1;67(Pt 8):o1875.