TargetMol

Clomipramine hydrochloride

Product Code:
 
TAR-T0255
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T0255-25mg25mg£96.00
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TAR-T0255-50mg50mg£103.00
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TAR-T0255-100mg100mg£111.00
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TAR-T0255-200mg200mg£120.00
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TAR-T0255-500mg500mg£136.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
Clomipramine hydrochloride is a tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
CAS:
17321-77-6
Formula:
C19H23ClN2?HCl
Molecular Weight:
351.31
Pathway:
Neuroscience; GPCR/G Protein; oxidation-reduction
Purity:
0.9947
SMILES:
Cl.CN(C)CCCN1c2ccccc2CCc2c1cc(Cl)cc2
Target:
Dopamine Receptor; 5-HT Receptor; Serotonin Transporter; Norepinephrine; GST

References

1. McTavish, D. and P. Benfield, Clomipramine. An overview of its pharmacological properties and a review of its therapeutic use in obsessive compulsive disorder and panic disorder. Drugs, 1990. 39(1): p. 136-53. 2. Ortiz, J. and F. Artigas, Effects of monoamine uptake inhibitors on extracellular and platelet 5-hydroxytryptamine in rat blood: different effects of clomipramine and fluoxetine. Br J Pharmacol, 1992. 105(4): p. 941-6. 3. Owens, M.J., et al., Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J Pharmacol Exp Ther, 1997. 283(3): p. 1305-22.