TargetMol

AZD-8529

Product Code:
 
TAR-T10432
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10432-5mg5mg£390.00
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TAR-T10432-50mg50mg£1,934.00
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Quantity:
TAR-T10432-100mg100mg£2,898.00
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This product comes from: United States.
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Further Information

Bioactivity:
AZD-8529 is a highly selective, and orally bioavailable positive allosteric modulator of mGluR2 (EC50: 285 nM). It shows no positive allosteric modulator responses at 20-25 M on the mGluR1, 3, 4, 5, 6, 7, and 8 subtypes.
CAS:
1092453-15-0
Formula:
C24H24F3N5O3
Molecular Weight:
487.483
Purity:
0.98
SMILES:
Cc1cc(cc2CN(Cc3ccc(OC(F)(F)F)cc3)C(=O)c12)-c1nc(CN2CCNCC2)no1

References

1. Justinova Z, et al. The Novel Metabotropic Glutamate Receptor 2 Positive Allosteric Modulator, AZD8529, Decreases Nicotine Self-Administration and Relapse in Squirrel Monkeys. Biol Psychiatry. 2015 Oct 1;78(7):452-62.