TargetMol

BM635

Product Code:
 
TAR-T10563
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10563-5mg5mg£291.00
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TAR-T10563-50mg50mg£1,163.00
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Quantity:
TAR-T10563-100mg100mg£1,669.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
BM635 is an MmpL3 inhibitor with outstanding anti-mycobacterial activity (MIC50: 0.12 μM against M. tuberculosis H37Rv).
CAS:
1493762-74-5
Formula:
C25H29FN2O
Molecular Weight:
392.518
Purity:
0.98
SMILES:
CC(C)c1ccc(cc1)-c1cc(CN2CCOCC2)c(C)n1-c1ccc(F)cc1

References

1. Poce G, et al. Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection. PLoS One. 2013;8(2):e56980. 2. Poce G, et al. Pharmaceutical salt of BM635 with improved bioavailability. Eur J Pharm Sci. 2017 Mar 1;99:17-23.