TargetMol

Desethyl chloroquine diphosphate

Product Code:
 
TAR-T11001L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11001L-25mg25mg£650.00
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TAR-T11001L-50mg50mg£1,002.00
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Quantity:
TAR-T11001L-100mg100mg£1,564.00
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This product comes from: United States.
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Further Information

Bioactivity:
Desethyl chloroquine diphosphate is the main deethyl metabolite of chloroquine. Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors (TLRs). Chloroquine diphosphate has anti-plasma activity.
CAS:
247912-76-1
Formula:
C16H28ClN3O8P2
Molecular Weight:
487.81
Purity:
0.98
SMILES:
OP(O)(O)=O.OP(O)(O)=O.CCNCCCC(C)Nc1ccnc2cc(Cl)ccc12

References

1. Ajayi FO, et al. Comparison of the partitioning in vitro of chloroquine and its desethyl metabolites between the erythrocytes and plasma of healthy subjects and those with falciparum malaria. Afr J Med Med Sci. 1989 Jun;18(2):95-100. 2. Vodicka P, et al. Assessment of chloroquine treatment for modulating autophagy flux in brain of WT and HD mice. J Huntingtons Dis. 2014;3(2):159-74. 3. Said A, et al. Chloroquine promotes IL-17 production by CD4+ T cells via p38-dependent IL-23 release by monocyte-derived Langerhans-like cells. J Immunol. 2014 Dec 15;193(12):6135-43.