TargetMol

DMT1 blocker 1

Product Code:
 
TAR-T11063
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11063-1mg1mg£179.00
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TAR-T11063-5mg5mg£303.00
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TAR-T11063-1mL1 mL * 10 mM (in DMSO)£426.00
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TAR-T11063-10mg10mg£454.00
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TAR-T11063-25mg25mg£704.00
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TAR-T11063-50mg50mg£938.00
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Quantity:
TAR-T11063-100mg100mg£1,259.00
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Quantity:
TAR-T11063-500mg500mg£2,456.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
DMT1 blocker 1 is a blocker of divalent metal transporter 1 (DMT1) with IC50 of 0.64 μM, which is expected to block the absorption of iron by intestinal cells in vivo.
CAS:
1354790-56-9
Formula:
C16H14N4O2
Molecular Weight:
294.31
Purity:
0.98
SMILES:
O=C(NC=1C=CC=CC1)C2=C(O)N(N=C2C)C3=NC=CC=C3

References

Cadieux JA, et al. Synthesis and biological evaluation of substituted pyrazoles as blockers of divalent metal transporter 1 (DMT1). Bioorg Med Chem Lett. 2012 Jan 1;22(1):90-5.