TargetMol

FTI 276 TFA

Product Code:
 
TAR-T11331
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11331-5mg5mg£337.00
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Quantity:
TAR-T11331-50mg50mg£1,532.00
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Quantity:
TAR-T11331-100mg100mg£2,287.00
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This product comes from: United States.
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Further Information

Bioactivity:
FTI 276 TFA is effective against plasmodium falciparum and humans.It is a protein-based nikyltransferase (PFT) inhibitor with an IC50s of 0.9 nM and 0.5 nM, respectively.
CAS:
1217471-51-6
Formula:
C23H28F3N3O5S2
Molecular Weight:
547.61
Purity:
0.98
SMILES:
OC(=O)C(F)(F)F.CSCC[C@H](NC(=O)c1ccc(NC[C@@H](N)CS)cc1-c1ccccc1)C(O)=O

References

1. Chakrabarti D, et al. Protein farnesyltransferase and protein prenylation in Plasmodium falciparum.J Biol Chem. 2002 Nov 1; 277(44):42066-73. Epub 2002 Aug 22.