TargetMol

LysRs-IN-2

Product Code:
 
TAR-T11920
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11920-5mg5mg£341.00
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Quantity:
TAR-T11920-50mg50mg£1,187.00
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Quantity:
TAR-T11920-100mg100mg£1,749.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
LysRs-IN-2 is a lysyl-tRNA synthetase (KRS) inhibitor with IC50s of 0.13 μM and 0.015 μM for Cryptosporidium parvum lysyl-tRNA synthetase (CpKRS) and Plasmodium falciparum lysyl-tRNA synthetase (PfKRS), respectively.
CAS:
2170696-76-9
Formula:
C17H16F3NO4
Molecular Weight:
355.313
Purity:
0.98
SMILES:
OC1(CNC(=O)c2cc(=O)c3cc(F)ccc3o2)CCC(F)(F)CC1

References

1. Baraga?a B, et al. Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis. Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):7015-7020.