TargetMol

Malic enzyme inhibitor ME1

Product Code:
 
TAR-T11940
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11940-1mg1mg£124.00
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TAR-T11940-1mL1 mL * 10 mM (in DMSO)£198.00
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TAR-T11940-5mg5mg£230.00
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TAR-T11940-10mg10mg£362.00
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TAR-T11940-25mg25mg£565.00
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TAR-T11940-50mg50mg£775.00
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Quantity:
TAR-T11940-100mg100mg£1,018.00
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Quantity:
TAR-T11940-500mg500mg£1,990.00
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This product comes from: United States.
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Further Information

Bioactivity:
Malic enzyme inhibitor ME1 is a potent inhibitor of Malic enzyme (ME1,IC50: 0.15μM).
CAS:
522649-59-8
Formula:
C20H21N3O3
Molecular Weight:
351.4
Purity:
0.98
SMILES:
O=C(C(N1CCN(C2=CC=C(O)C=C2)CC1)C3)N(C4=CC=CC=C4)C3=O

References

1. Zhang YJ, et al. In silico design and synthesis of piperazine-1-pyrrolidine-2,5-dione scaffold-based novel malic enzyme inhibitors. Bioorg Med Chem Lett. 2006 Feb;16(3):525-8. Epub 2005 Nov 8. 2. Fernandes L, et al. Malic Enzyme 1 (ME1) is pro-oncogenic in ApcMin/+ mice. Sci Rep. 2018 Sep 24;8(1):14268.