TargetMol

FT671

Product Code:
 
TAR-T12621L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12621L-5mg5mg£1,171.00
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TAR-T12621L-50mg50mg£2,303.00
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Quantity:
TAR-T12621L-100mg100mg£3,042.00
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This product comes from: United States.
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Further Information

Bioactivity:
FT671 is a non-covalent and selective inhibitor of USP7 (IC50: 52 nM) It also binds to the USP7 catalytic domain (Kd: 65 nM).
CAS:
1959551-26-8
Formula:
C24H23F4N7O3
Molecular Weight:
533.488
Pathway:
Ubiquitination; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Purity:
0.98
SMILES:
OC1(Cn2cnc3n(ncc3c2=O)-c2ccc(F)cc2)CCN(CC1)C(=O)C[C@@H](C(F)F)n1ccc(F)n1
Target:
DUB

References

1. Turnbull AP, et al. Molecular basis of USP7 inhibition by selective small-molecule inhibitors. Nature. 2017 Oct 26;550(7677):481-486.