TargetMol

TMPyP4 tosylate

Product Code:
 
TAR-T13174
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13174-25mg25mg£108.00
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TAR-T13174-50mg50mg£125.00
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TAR-T13174-100mg100mg£148.00
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This product comes from: United States.
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Further Information

Bioactivity:
TMPyP4 tosylate is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.
CAS:
36951-72-1
Formula:
C72H66N8O12S4
Molecular Weight:
1363.6
Pathway:
Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Purity:
0.9911
SMILES:
Cc1ccc(cc1)S([O-])(=O)=O.Cc1ccc(cc1)S([O-])(=O)=O.Cc1ccc(cc1)S([O-])(=O)=O.Cc1ccc(cc1)S([O-])(=O)=O.C[n+]1ccc(cc1)-c1c2ccc(n2)c(-c2cc[n+](C)cc2)c2ccc([nH]2)c(-c2cc[n+](C)cc2)c2ccc(n2)c(-c2cc[n+](C)cc2)c2ccc1[nH]2
Target:
DNA/RNA Synthesis; Telomerase

References

1. Fujimori J, et al. Antitumor effects of telomerase inhibitor TMPyP4 in osteosarcoma cell lines. J Orthop Res. 2011 Nov;29(11):1707-11. 2. Chen H, et al. Insuline-like growth factor type I selectively binds to G-quadruplex structures. Biochim Biophys Acta Gen Subj. 2019 Jan;1863(1):31-38.