TargetMol

Tyk2-IN-8

Product Code:
 
TAR-T13237L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13237L-1mg1mg£266.00
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Quantity:
TAR-T13237L-2mg2mg£364.00
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TAR-T13237L-5mg5mg£487.00
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TAR-T13237L-10mg10mg£672.00
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Quantity:
TAR-T13237L-25mg25mg£1,002.00
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Quantity:
TAR-T13237L-50mg50mg£1,332.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
Tyk2-IN-8 is a selective TYK2 inhibitor, which binds to TYK2 catalytically active JH1 domain (IC50: 17 nM).
CAS:
2127109-84-4
Formula:
C20H17N9
Molecular Weight:
383.419
Pathway:
Tyrosine Kinase/Adaptors
Purity:
0.98
SMILES:
Cn1cc(cn1)-c1cn2nccc2c(n1)-c1cnn(c1)[C@@]1(CC#N)C[C@@H](C1)C#N
Target:
Tyrosine Kinases

References

Wrobleski ST, et al. Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165. J Med Chem. 2019 Jul 18.