TargetMol

SCH00013

Product Code:
 
TAR-T13882
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13882-5mg5mg£351.00
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TAR-T13882-50mg50mg£1,131.00
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Quantity:
TAR-T13882-100mg100mg£1,669.00
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Further Information

Bioactivity:
SCH00013 is an agent of cardiotonic that primarily acts via an increase in myofibrillar Ca++ sensitivity. SCH00013 have a significant Ca(2+)sensitizing effect at pH 7.2 to 7.4.
CAS:
217963-18-3
Formula:
C18H20N4O2
Molecular Weight:
324.384
Purity:
0.98
SMILES:
OC(CN1CCC(=CC1)C1=NNC(=O)CC1)c1ccc(cc1)C#N

References

1. Sugawara H et al. A novel cardiotonic agent SCH00013 acts as a Ca++ sensitizer with no chronotropic activity in mammalian cardiac muscle. J Pharmacol Exp Ther. 1998 Oct;287(1):214-22. 2. Tadano N et al. SCH00013, a novel Ca(2+) sensitizer with positive inotropic and no chronotropic action in heart failure. J Pharmacol Sci. 2005 Jan;97(1):53-60. 3. Endoh M et al. Pharmacology of SCH00013: a novel Ca2+ sensitizer. Cardiovasc Drug Rev. 2001 Winter;19(4):345-66.