TargetMol

Methotrexate

Product Code:
 
TAR-T1485
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1485-50mg50mg£101.00
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Quantity:
TAR-T1485-1mL1 mL * 10 mM (in DMSO)£114.00
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Quantity:
TAR-T1485-100mg100mg£114.00
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TAR-T1485-200mg200mg£136.00
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Quantity:
TAR-T1485-500mg500mg£185.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Methotrexate is a folate analog metabolic inhibitor with immunosuppressant and antineoplastic properties.
CAS:
59-05-2
Formula:
C20H22N8O5
Molecular Weight:
454.447
Pathway:
Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Apoptosis
Purity:
0.9946
SMILES:
CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
Target:
Apoptosis; Dehydrogenase; DNA/RNA Synthesis; Antifolate

References

1. Genestier L, et al. J Clin Invest, 1998, 102(2), 322-328. 2. Chan ES, et al. Arthritis Res, 2002, 4(4), 266-273. 3. Cronstein BN, et al. J Clin Invest, 1993, 92(6), 2675-2682. 4. Bennett BC, et al. J Med Chem. 2007, 50(18):4374-81.