TargetMol

D5D-IN-326

Product Code:
 
TAR-T15043
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15043-5mg5mg£351.00
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TAR-T15043-50mg50mg£1,564.00
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Quantity:
TAR-T15043-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
D5D-IN-326 is an orally active delta-5 desaturase (D5D) inhibitor (IC50s: 72 and 22 nM for rat and human D5D in enzymic and cell-based assays). It has no effect on D6D or D9D activity. D5D-IN-326 reduces insulin resistance and decreases body weight in diet-induced obese C57BL/6J mice.
CAS:
1236767-85-3
Formula:
C17H11F8N3O4
Molecular Weight:
473.279
Purity:
0.98
SMILES:
FC(F)(F)COc1ccc(cc1)-n1c(OCC(F)(F)C(F)(F)F)nc2NC(=O)Cc2c1=O

References

1. Yashiro H, et al. A Novel Selective Inhibitor of Delta-5 Desaturase Lowers Insulin Resistance and Reduces Body Weight in Diet-Induced Obese C57BL/6J Mice. PLoS One. 2016 Nov 10;11(11):e0166198.