TargetMol

GS-626510

Product Code:
 
TAR-T15419
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15419-5mg5mg£270.00
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TAR-T15419-50mg50mg£1,026.00
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Quantity:
TAR-T15419-100mg100mg£1,564.00
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This product comes from: United States.
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Further Information

Bioactivity:
GS-626510 is an orally bioavailable inhibitor of BET family bromodomains (Kd: 0.59-3.2 nM for BRD2/3/4; IC50: 83 nM and 78 nM for BD1 and BD2).
CAS:
1637770-13-8
Formula:
C25H22N4O
Molecular Weight:
394.478
Pathway:
Chromatin/Epigenetic
Purity:
0.98
SMILES:
Cc1noc(C)c1-c1cc(-c2c(C)ccc3ncccc23)c2[nH]c(nc2c1)C1CC1
Target:
Epigenetic Reader Domain

References

1. Sperandio D, et al. Structure-guided discovery of a novel, potent, and orally bioavailable 3,5-dimethylisoxazole aryl-benzimidazole BET bromodomain inhibitor. Bioorg Med Chem. 2019 Feb 1;27(3):457-469.