TargetMol

Inolitazone dihydrochloride

Product Code:
 
TAR-T15580
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15580-5mg5mg£270.00
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TAR-T15580-50mg50mg£1,187.00
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Quantity:
TAR-T15580-100mg100mg£1,854.00
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This product comes from: United States.
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Further Information

Bioactivity:
Inolitazone dihydrochloride is a novel high-affinity agonist of PPARγ. It is dependent upon PPARγ for its biological activity (IC50: 0.8 nM for growth inhibition).
CAS:
223132-38-5
Formula:
C27H28Cl2N4O4S
Molecular Weight:
575.51
Pathway:
Metabolism; DNA Damage/DNA Repair
Purity:
0.98
SMILES:
Cl.Cl.Cc1cc(Oc2ccc3nc(COc4ccc(CC5SC(=O)NC5=O)cc4)n(C)c3c2)cc(C)c1N
Target:
PPAR

References

1. Copland JA, et al. Novel high-affinity PPARgamma agonist alone and in combination with paclitaxel inhibits human anaplastic thyroid carcinoma tumor growth via p21WAF1/CIP1. Oncogene. 2006 Apr 13;25(16):2304-17. 2. Marlow LA, et al. Reactivation of suppressed RhoB is a critical step for the inhibition of anaplastic thyroid cancer growth. Cancer Res. 2009 Feb 15;69(4):1536-44.