TargetMol

ONO-5334

Product Code:
 
TAR-T16394
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16394-5mg5mg£404.00
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Quantity:
TAR-T16394-50mg50mg£1,348.00
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Quantity:
TAR-T16394-100mg100mg£2,014.00
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This product comes from: United States.
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Further Information

Bioactivity:
ONO-5334 is an effective and selective cathepsin K inhibitor (Ki: 0.10 nM, 0.049 nM, and 0.85 nM for human, rabbit, and rat cathepsin K, respectively). ONO-5334 has the potential for the study of osteoporosis.
CAS:
868273-90-9
Formula:
C21H34N4O4S
Molecular Weight:
438.59
Pathway:
Proteases/Proteasome
Purity:
0.98
SMILES:
C[C@@H]1CSC(=N/NC(=O)C(=O)[C@@H](NC(=O)C2CCCCCC2)C2CCOCC2)N1C
Target:
Cysteine Protease

References

1. Ochi Y, et al. Effects of ONO-5334, a novel orally-active inhibitor of cathepsin K, on?bone?metabolism. Bone.?2011?Dec;49(6):1351-6.