Rotigaptide

Product Code:

TAR-T16790

Product Group:

Inhibitors and Activators

Supplier:

TargetMol

Regulatory Status:

RUO

Shipping:

cool pack

Storage:

-20℃

No additional charges, what you see is what you pay! *

Code	Size	Price

TAR-T16790-25mg

25mg

£837.00

Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.

Quantity:

Prices exclude any Taxes / VAT

How to order with us Contact us

Further Information

Bioactivity:

Rotigaptide is a novel and specific modulator of Cx43 and is a potent AAP. Rotigaptide prevents the uncoupling of Cx43-mediated gap junction communication and normalizes cell-to-cell communication during acute metabolic stress.

CAS:

355151-12-1

Formula:

C28H39N7O9

Molecular Weight:

617.66

Purity:

0.98

SMILES:

C[C@@H](NC(=O)CNC(=O)[C@H]1C[C@H](O)CN1C(=O)[C@H]1CCCN1C(=O)[C@@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)NCC(N)=O

Documents

References

1. Seyed Mojtaba?Ghiasi, et al. The connexin 43 regulator Rotigaptide reduces cytokine-induced cell death in human islets 2. Stahlhut M, et al. The antiarrhythmic peptide rotigaptide (ZP123) increases connexin 43 protein expression in neonatal rat ventricular cardiomyocytes.Cell Commun Adhes.?2006 Jan-Apr;13(1-2):21-7. 3. Kj?lbye AL, et al. Pharmacological?modulation?of?gap?junction?function?with the?novel?compound?rotigaptide: a?promising?new?principle?for?prevention?of?arrhythmias.Basic Clin Pharmacol Toxicol.?2007 Oct;101(4):215-30.