TargetMol

ERDRP-0519

Product Code:
 
TAR-T24040
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24040-1mg1mg£182.00
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TAR-T24040-5mg5mg£349.00
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Quantity:
TAR-T24040-1mL1 mL * 10 mM (in DMSO)£377.00
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TAR-T24040-10mg10mg£462.00
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TAR-T24040-25mg25mg£701.00
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TAR-T24040-50mg50mg£970.00
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Quantity:
TAR-T24040-100mg100mg£1,259.00
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This product comes from: United States.
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Further Information

Bioactivity:
ERDRP-0519 is an orally available inhibitor of the polymerase.
CAS:
1374006-96-8
Formula:
C23H30F3N5O4S
Molecular Weight:
529.58
Pathway:
Immunology/Inflammation
Purity:
0.98
SMILES:
Cn1nc(cc1C(=O)Nc1ccc(cc1)S(=O)(=O)N1CCCC[C@H]1CCN1CCOCC1)C(F)(F)F
Target:
Antiviral

References

Stefanie A Krumm, et al. An orally available, small-molecule polymerase inhibitor shows efficacy against a lethal morbillivirus infection in a large animal model. Sci Transl Med. 2014 Apr 16;6(232):232ra52. Richard K Plemper. Measles Resurgence and Drug Development. Curr Opin Virol. 2020 Apr;41:8-17. Kevin Wittwer, et al. Small-molecule polymerase inhibitor protects non-human primates from measles and reduces shedding. Nat Commun. 2021 Sep 2;12(1):5233.