TargetMol

VPC-14449

Product Code:
 
TAR-T24944
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24944-5mg5mg£270.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T24944-50mg50mg£871.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T24944-100mg100mg£1,307.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
VPC-14449 is a specific inhibitor of AR-DBD that acts by inhibiting both Y594A and Q592A mutants.
CAS:
1621375-32-3
Formula:
C10H10Br2N4OS
Molecular Weight:
394.09
Purity:
0.98
SMILES:
Brc1ncn(c1Br)-c1csc(n1)N1CCOCC1

References

1. Dalal K, Roshan-Moniri M, Sharma A, Li H, Ban F, Hassona MD, Hsing M, Singh K, LeBlanc E, Dehm S, Tomlinson Guns ES, Cherkasov A, Rennie PS. Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer. J Biol Chem. 2014 Sep 19;289(38):26417-29. doi: 10.1074/jbc.M114.553818. Epub 2014 Aug 1. Erratum in: J Biol Chem. 2015 Oct 23;290(43):25850. J Biol Chem. 2014 Dec 5;289(49):33877. Hessein, Mohamed [Corrected to Hassona, Mohamed D]. J Biol Chem. 2017 Mar 10;292(10 ):4359. PubMed PMID: 25086042; PubMed Central PMCID: PMC4176249.