TargetMol

Jmv 390-1

Product Code:
 
TAR-T25554
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T25554-5mg5mg£850.00
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TAR-T25554-50mg50mg£1,661.00
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Quantity:
TAR-T25554-100mg100mg£2,079.00
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  • Further Information
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Further Information

Bioactivity:
Jmv 390-1 is an inhibitor of metallopeptidase.
CAS:
148473-36-3
Formula:
C23H35N3O6
Molecular Weight:
449.548
Purity:
0.98
SMILES:
CC[C@H](C)[C@H](NC(=O)[C@@H](CC(=O)NO)Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(O)=O

References

1. Kitabgi P, Dubuc I, Nouel D, Costentin J, Cuber JC, Fulcrand H, Doulut S, Rodriguez M, Martinez J. Effects of thiorphan, bestatin and a novel metallopeptidase inhibitor JMV 390-1 on the recovery of neurotensin and neuromedin N released from mouse hypothalamus. Neurosci Lett. 1992 Aug 17;142(2):200-4. PubMed PMID: 1454216. 2. Marshall AC, Pirro NT, Rose JC, Diz DI, Chappell MC. Evidence for an angiotensin-(1-7) neuropeptidase expressed in the brain medulla and CSF of sheep. J Neurochem. 2014 Jul;130(2):313-23. doi: 10.1111/jnc.12720. Epub 2014 Apr 19. PubMed PMID: 24661079; PubMed Central PMCID: PMC4137327. 3. Cruz-Diaz N, Wilson BA, Pirro NT, Brosnihan KB, Marshall AC, Chappell MC. Identification of dipeptidyl peptidase 3 as the Angiotensin-(1-7) degrading peptidase in human HK-2 renal epithelial cells. Peptides. 2016 Sep;83:29-37. doi: 10.1016/j.peptides.2016.06.005. Epub 2016 Jun 15. PubMed PMID: 27315786; PubMed Central PMCID: PMC5500233. 4. Yilmaz EM, G?ntert P. NMR structure calculation for all small molecule ligands and non-standard residues from the PDB Chemical Component Dictionary. J Biomol NMR. 2015 Sep;63(1):21-37. doi: 10.1007/s10858-015-9959-y. Epub 2015 Jun 30. PubMed PMID: 26123317.