TargetMol

AS1708727

Product Code:
 
TAR-T26661
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26661-5mg5mg£270.00
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Quantity:
TAR-T26661-50mg50mg£1,026.00
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Quantity:
TAR-T26661-100mg100mg£1,564.00
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This product comes from: United States.
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Further Information

Bioactivity:
AS1708727 is a Foxo1 inhibitor, exerting anti-hypertriglyceridemic and anti-diabetic effects by improving triglyceride and blood glucose metabolism at the gene expression level.
CAS:
1253226-93-5
Formula:
C24H24Cl2N2O2
Molecular Weight:
443.37
Purity:
0.98
SMILES:
CN(C(=O)CC1CCCC1)c1ccc(Cl)c(COc2cccc3cnccc23)c1Cl

References

1. Tanaka H, Nagashima T, Shimaya A, Urano Y, Shimokawa T, Shibasaki M. Effects of the novel Foxo1 inhibitor AS1708727 on plasma glucose and triglyceride levels in diabetic db/db mice. Eur J Pharmacol. 2010 Oct 25;645(1-3):185-91. doi: 10.1016/j.ejphar.2010.07.018. Epub 2010 Jul 23. PubMed PMID: 20655898.