TargetMol

(S)-10-Hydroxycamptothecin

Product Code:
 
TAR-T2764
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2764-25mg25mg£108.00
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Quantity:
TAR-T2764-1mL1 mL * 10 mM (in DMSO)£116.00
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TAR-T2764-50mg50mg£119.00
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Quantity:
TAR-T2764-100mg100mg£138.00
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This product comes from: United States.
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Further Information

Bioactivity:
10-Hydroxycamptothecin is a DNA topoisomerase I inhibitor, utilized as a clinical therapy agent against hepatoma.
CAS:
19685-09-7
Formula:
C20H16N2O5
Molecular Weight:
364.36
Pathway:
Apoptosis; DNA Damage/DNA Repair
Purity:
0.9981
SMILES:
CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4ccc(O)cc4cc3Cn1c2=O
Target:
Apoptosis; Topoisomerase

References

1. Ling YH, et al. Cancer Biochem Biophys, 1990, 11(1), 23-30. 2. Vladu B, et al. Mol Pharmacol, 2000, 57(2), 243-251. 3. Xiao D, et al. Life Sci, 2001, 69(14), 1619-1628. 4. Ping YH, et al. Oncol Rep, 2006, 15(5), 1273-1279.