TargetMol

KB-130015

Product Code:
 
TAR-T27713
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27713-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T27713-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T27713-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
KB-130015, a activator of hERG1 potassium channels, blocks native and recombinant hERG1 channels at high voltages.
CAS:
147030-48-6
Formula:
C18H14I2O4
Molecular Weight:
548.115
Purity:
0.98
SMILES:
Cc1oc2ccccc2c1Cc1cc(I)c(OCC(O)=O)c(I)c1

References

1. Gessner G, Macianskiene R, Starkus JG, Sch?nherr R, Heinemann SH. The amiodarone derivative KB130015 activates hERG1 potassium channels via a novel mechanism. Eur J Pharmacol. 2010 Apr 25;632(1-3):52-9. doi: 10.1016/j.ejphar.2010.01.010. PubMed PMID: 20097192; PubMed Central PMCID: PMC2835770. 2. Borchard R, van Bracht M, Wickenbrock I, Prull MW, Pott L, Trappe HJ. [Inhibition of the muscarinic potassium current by KB130015, a new antiarrhythmic agent to treat atrial fibrillation]. Med Klin (Munich). 2005 Nov 15;100(11):697-703. German. PubMed PMID: 16328176.