TargetMol

RYL-552

Product Code:
 
TAR-T28636
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T28636-5mg5mg£331.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T28636-50mg50mg£1,396.00
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Quantity:
TAR-T28636-100mg100mg£2,079.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
RYL-552 is a potent inhibitor of PfNDH2.
CAS:
1801444-56-3
Formula:
C24H17F4NO2
Molecular Weight:
427.399
Purity:
0.98
SMILES:
Cc1c([nH]c2cccc(F)c2c1=O)-c1ccc(Cc2ccc(OC(F)(F)F)cc2)cc1

References

1. Yang Y, Yu Y, Li X, Li J, Wu Y, Yu J, Ge J, Huang Z, Jiang L, Rao Y, Yang M. Target Elucidation by Cocrystal Structures of NADH-Ubiquinone Oxidoreductase of Plasmodium falciparum (PfNDH2) with Small Molecule To Eliminate Drug-Resistant Malaria. J Med Chem. 2017 Mar 9;60(5):1994-2005. doi: 10.1021/acs.jmedchem.6b01733. Epub 2017 Feb 22. PubMed PMID: 28195463.