TargetMol

S-5751

Product Code:
 
TAR-T28651
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28651-5mg5mg£930.00
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TAR-T28651-50mg50mg£1,821.00
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Quantity:
TAR-T28651-100mg100mg£2,319.00
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This product comes from: United States.
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Further Information

Bioactivity:
S-5751, a prostanoid DP (DP1) antagonist, is used potentially for the treatment of bronchial asthma.
CAS:
209268-36-0
Formula:
C25H31NO4S
Molecular Weight:
441.59
Purity:
0.98
SMILES:
[H][C@@]12C[C@@]([H])([C@H](NC(=O)c3csc4ccc(O)cc34)[C@@H](CC=C/CCCC(O)=O)C1)C2(C)C

References

1. Arimura A, Yasui K, Kishino J, Asanuma F, Hasegawa H, Kakudo S, Ohtani M, Arita H. Prevention of allergic inflammation by a novel prostaglandin receptor antagonist, S-5751. J Pharmacol Exp Ther. 2001 Aug;298(2):411-9. PubMed PMID: 11454901. 2. Shichijo M, Arimura A, Hirano Y, Yasui K, Suzuki N, Deguchi M, Abraham WM. A prostaglandin D2 receptor antagonist modifies experimental asthma in sheep. Clin Exp Allergy. 2009 Sep;39(9):1404-14. doi: 10.1111/j.1365-2222.2009.03275.x. PubMed PMID: 19486034. 3. Hirano Y, Shichijo M, Ikeda M, Kitaura M, Tsuchida J, Asanuma F, Yanagimoto T, Furue Y, Imura K, Yasui K, Arimura A. Prostanoid DP receptor antagonists suppress symptomatic asthma-like manifestation by distinct actions from a glucocorticoid in rats. Eur J Pharmacol. 2011 Sep;666(1-3):233-41. doi: 10.1016/j.ejphar.2011.05.003. PubMed PMID: 21596028. 4. Yasui K, Asanuma F, Hirano Y, Shichijo M, Deguchi M, Arimura A. Contribution of prostaglandin D2 via prostanoid DP receptor to nasal hyperresponsiveness in guinea pigs repeatedly exposed to antigen. Eur J Pharmacol. 2008 Jan 14;578(2-3):286-91. PubMed PMID: 17927976.