TargetMol

Emodin

Product Code:
 
TAR-T2869
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2869-50mg50mg£107.00
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Quantity:
TAR-T2869-1mL1 mL * 10 mM (in DMSO)£111.00
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Further Information

Bioactivity:
Emodin is a naturally occurring anthraquinone present in the roots and barks of numerous plants; exerts antiproliferative effects in Y cells that are regulated by different signaling pathways.
CAS:
518-82-1
Formula:
C15H10O5
Molecular Weight:
270.24
Pathway:
Autophagy; Metabolism; Stem Cells; Microbiology/Virology
Purity:
0.944
SMILES:
Cc1cc(O)c2C(=O)c3c(O)cc(O)cc3C(=O)c2c1
Target:
SARS-CoV; Casein Kinase; Autophagy

References

1. Yim H, et al. Emodin, an anthraquinone derivative isolated from the rhizomes of Rheum palmatum, selectively inhibits the activity of casein kinase II as a competitive inhibitor. Planta Med. 1999 Feb;65(1):9-13. 2. Xing JY, et al. Antitumor Effects and Mechanism of Novel Emodin Rhamnoside Derivatives against Human Cancer CellsIn Vitro. PLoS One. 2015 Dec 18;10(12):e20144781. 3. Li X, et al. Emodin enhances cisplatin-induced cytotoxicity in human bladder cancer cells through ROS elevation and MRP1 downregulation. BMC Cancer. 2016 Aug 2;16:578. 5. Costa M, Rosa F, Ribeiro T, et al. Identification of Cyanobacterial Strains with Potential for the Treatment of Obesity-Related Co-Morbidities by Bioactivity, Toxicity Evaluation and Metabolite Profiling[J]. Marine drugs. 2019 May 10;17(5).