TargetMol

Fasudil hydrochloride

Product Code:
 
TAR-T3060
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3060-50mg50mg£99.00
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TAR-T3060-100mg100mg£107.00
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TAR-T3060-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T3060-200mg200mg£125.00
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TAR-T3060-500mg500mg£148.00
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This product comes from: United States.
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Further Information

Bioactivity:
Fasudil Hydrochloride is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.
CAS:
105628-07-7
Formula:
C14H18ClN3O2S
Molecular Weight:
327.83
Pathway:
Metabolism; Microbiology/Virology; Autophagy; Tyrosine Kinase/Adaptors; Membrane transporter/Ion channel; Chromatin/Epigenetic; Cytoskeletal Signaling; Proteases/Proteasome; Stem Cells; Cell Cycle/Checkpoint
Purity:
0.9998
SMILES:
Cl.O=S(=O)(N1CCCNCC1)c1cccc2cnccc12
Target:
ROCK; Serine/threonin kinase; Calcium Channel; HIV Protease; PKA; PKC; Autophagy

References

1. Ono-Saito N, et al. Pharmacol Ther, 1999, 82(2-3), 123-131. 2. Asano T, et al. J Pharmacol Exp Ther, 1987, 241(3), 1033-1040. 3. Asano T, et al. Br J Pharmacol, 1989, 98(4), 1091-1100. 4. Negoro N, et al. Biochem Biophys Res Commun, 1999, 262(1), 211-215. 5. Fukushima M, et al. Liver Int, 2005, 25(4), 829-838.