TargetMol

GSK-3β inhibitor 3

Product Code:
 
TAR-T35554
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T35554-1mg1mg£149.00
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TAR-T35554-5mg5mg£269.00
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TAR-T35554-1mL1 mL * 10 mM (in DMSO)£289.00
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TAR-T35554-10mg10mg£386.00
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TAR-T35554-25mg25mg£600.00
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TAR-T35554-50mg50mg£825.00
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TAR-T35554-100mg100mg£1,091.00
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TAR-T35554-500mg500mg£2,119.00
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Further Information

Bioactivity:
GSK-3β inhibitor 3 is a potent, selective, irreversible and covalent inhibitor of Glycogen Synthase Kinase 3β (GSK-3β), with an IC50 of 6.6 μM. GSK-3β inhibitor 3 can be used for the research of acute promyelocytic leukemia[1].
CAS:
1448990-73-5
Formula:
C18H14FNO2S
Molecular Weight:
327.37
Pathway:
Apoptosis|Stem Cells|PI3K/Akt/mTOR signaling
Purity:
0.98
SMILES:
N/A
Target:
Apoptosis|GSK-3

References

Zhang P, et al. Discovery of Novel Benzothiazepinones as Irreversible Covalent Glycogen Synthase Kinase 3? Inhibitors for the Treatment of Acute Promyelocytic Leukemia. J Med Chem. 2021;64(11):7341-7358.