TargetMol

Pyridoxal phosphate

Product Code:
 
TAR-T3578
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3578-100mg100mg£104.00
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TAR-T3578-200mg200mg£106.00
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TAR-T3578-1g1g£117.00
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Further Information

Bioactivity:
Pyridoxal Phosphate is the active form of vitamin B6 and a coenzyme for many pyridoxal phosphate (PLP)-dependent enzymes. PLP is involved in numerous enzymatic transamination, decarboxylation and deamination reactions; it is necessary for the synthesis of amino acids and amino acid metabolites, and for the synthesis and/or catabolism of certain neurotransmitters, including the conversion of glutamate into gamma-aminobutyric acid (GABA) and levodopa into dopamine. PLP can be used as a dietary supplement in cases of vitamin B6 deficiency. Reduced levels of PLP in the brain can cause neurological dysfunction.
CAS:
54-47-7
Formula:
C8H10NO6P
Molecular Weight:
247.14
Pathway:
Microbiology/Virology; Metabolism
Purity:
0.9945
SMILES:
Cc1ncc(c(c1O)C=O)COP(=O)(O)O
Target:
Reverse Transcriptase; Endogenous Metabolite

References

Modak MJ. Pyridoxal 5' phosphate: a selective inhibitor of oncornaviral DNA polymerases. Biochem Biophys Res Commun. 1976 Jul 12;71(1):180-7. Grin IR, et al. Inactivation of NEIL2 DNA glycosylase by pyridoxal phosphate reveals a loop important for substrate binding. Biochem Biophys Res Commun. 2010 Mar 26;394(1):100-5.