TargetMol

SEC

Product Code:
 
TAR-T36535
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T36535-5mg5mg£270.00
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Quantity:
TAR-T36535-50mg50mg£1,099.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T36535-100mg100mg£1,564.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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Further Information

Bioactivity:
SEC induces activation of ANXA7 GTPase via the AMPK/mTORC1/STAT3 signaling pathway. SEC selectively promotes apoptosis in cancer cells, expressing a high level of ITGB4 by inducing ITGB4 nuclear translocation[1][2].
CAS:
1802997-81-4
Formula:
C22H23ClN2O5
Molecular Weight:
430.88
Purity:
0.98
SMILES:
O=C(OCC)C1=CC(C2=CC=C(C=C2)OC)=NN1C[C@@H](COC3=CC=C(C=C3)Cl)O

References

ShuYan Liu, et al. A small molecule induces integrin ?4 nuclear translocation and apoptosis selectively in cancer cells with high expression of integrin ?4. Oncotarget. 2016 Mar 29; 7(13): 16282-16296. ShuYan Liu, et al. SEC-induced Activation of ANXA7 GTPase Suppresses Prostate Cancer Metastasis. Cancer Lett. 2018 Mar 1;416:11-23.