TargetMol

XTT (sodium salt hydrate)

Product Code:
 
TAR-T37583
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T37583-25mg25mg£124.00
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TAR-T37583-50mg50mg£176.00
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TAR-T37583-100mg100mg£259.00
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Further Information

Bioactivity:
XTT is a cell-impermeable, negatively charged tetrazolium dye that produces a water-soluble formazan when reduced at the cell surface by cellular-derived NADH and an electron mediator.1,2It is frequently used in colorimetric assays to measure cell proliferation, cytotoxicity, and apoptosis.3
CAS:
413585-64-5
Formula:
C22H16N7O13S2.Na [XH2O]
Molecular Weight:
650.5
Purity:
0.98
SMILES:
COC(C=C([N+]([O-])=O)C(S([O-])(=O)=O)=C1)=C1N2N=C(C(NC3=CC=CC=C3)=O)N=[N+]2C4=CC(S([O-])(=O)=O)=C([N+]([O-])=O)C=C4OC.[Na+].O

References

Berridge, M.V., and Tan, A.S.Trans-plasma membrane electron transport: A cellular assay for NADH-and NADPH-oxidase based on extracellular, superoxide-mediated reduction of the sulfonated tetazolium salt WST-1Protoplasma20574-82(1998) Berridge, M.V., Tan, A.S., and Herst, P.M.Tetrazolium dyes as tools in cell biology: New insights into their cellular reductionBiotechnol. Ann. Rev.11127-152(2005) Sutherland, M.W., and Learmonth, B.A.The tetrazolium dyes MTS and XTT provide new quantitative assays for superoxide and superoxide dismutaseFree Radical Research27(3)283-289(1997)