TargetMol

KRA-533

Product Code:
 
TAR-T38411
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T38411-25mg25mgEnquire
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TAR-T38411-50mg50mgEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
KRA-533 is a potent KRAS agonist. KRA-533 binds to the GTP/GDP binding pocket in the KRAS protein to prevent GTP cleavage, resulting in the accumulation of constitutively active GTP-bound KRAS that triggers both apoptotic and autophagic cell death pathways in cancer cells.
CAS:
10161-87-2
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0

References

Xu K, et al. Small Molecule KRAS Agonist for Mutant KRAS Cancer Therapy [published correction appears in Mol Cancer. 2020 May 20;19(1):93]. Mol Cancer. 2019;18(1):85. Published 2019 Apr 10.