TargetMol

TLR4-IN-C34-C2-COOH

Product Code:
 
TAR-T38547
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T38547-25mg25mg£123.00
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Quantity:
TAR-T38547-50mg50mg£148.00
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Quantity:
TAR-T38547-100mg100mg£204.00
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Quantity:
TAR-T38547-500mg500mg£412.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
TLR4-IN-C34-C2-COO is a linker that incorporates TLR4 inhibitor TLR4-IN-C34. TLR4-IN-C34 inhibits TLR4 in enterocytes and macrophages, and reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis.
CAS:
1159408-54-4
Formula:
C19H29NO11
Molecular Weight:
447.437
Purity:
0.98
SMILES:
CC(=O)N[C@H]1[C@H](OCCCCC(O)=O)O[C@H](COC(C)=O)[C@H](OC(C)=O)[C@@H]1OC(C)=O

References

Neal MD, et al. Discovery and validation of a new class of small molecule Toll-like receptor 4 (TLR4) inhibitors. PLoS One. 2013;8(6):e65779. Published 2013 Jun 12.