TargetMol

(S,R,S)-AHPC-C2-NH2 dihydrochloride

Product Code:
 
TAR-T39871
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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Further Information

Bioactivity:
(S,R,S)-AHPC-C2-NH2 dihydrochloride incorporates a VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. (S,R,S)-AHPC-OH can be used in the synthesis of a series of PROTACs.
CAS:
2341796-73-2
Formula:
C25H37Cl2N5O4S
Molecular Weight:
574.56
Purity:
0.98
SMILES:
Cl.Cl.Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCN)C(C)(C)C)cc1

References

Jing Liu, et al. Tropomyosin receptor kinase (trk) degradation compounds and methods of use. WO2020038415A1.