TargetMol

Dantrolene sodium hemiheptahydrate

Product Code:
 
TAR-T4054
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4054-100mg100mg£109.00
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TAR-T4054-1mL1 mL * 10 mM (in DMSO)£114.00
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TAR-T4054-500mg500mg£189.00
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This product comes from: United States.
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Further Information

Bioactivity:
Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1 and decreasing intracellular calcium concentration. Ryanodine receptors mediate the release of calcium from the sarcoplasmic reticulum, an essential step in muscle contraction. Dantrolene Sodium is the sodium salt form of dantrolene, a hydantoin derivative, and direct-acting skeletal muscle relaxant.
CAS:
24868-20-0
Formula:
C28H32N8Na2O17
Molecular Weight:
798.583
Pathway:
Membrane transporter/Ion channel; Metabolism; Autophagy
Purity:
0.9852
SMILES:
O.O.O.O.O.O.O.[Na+].[Na+].[O-][N+](=O)c1ccc(cc1)-c1ccc(C=NN2CC(=O)[N-]C2=O)o1.[O-][N+](=O)c1ccc(cc1)-c1ccc(C=NN2CC(=O)[N-]C2=O)o1
Target:
Calcium Channel; Autophagy

References

Leslie GC., et al. The action of dantrolene sodium on rat fast and slow muscle in vivo. Br J Pharmacol. 1981 Apr;72(4):665-72. B?y?kokuro?lu ME., et al. In vitro antioxidant properties of dantrolene sodium. Pharmacol Res. 2001 Dec;44(6):491-4.