TargetMol

Cycloleucine

Product Code:
 
TAR-T9626
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9626-25mg25mg£103.00
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TAR-T9626-50mg50mg£116.00
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TAR-T9626-100mg100mg£136.00
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TAR-T9626-200mg200mg£168.00
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TAR-T9626-500mg500mg£229.00
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This product comes from: United States.
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Further Information

Bioactivity:
Cycloleucine is an antagonist of NMDA receptor associated glycine receptor with a Ki of 600 μM. Cycloleucine is also a competitive inhibitor of S-adenosyl-methionine mediated methylation with anxiolytic and cytostatic effects.
CAS:
52-52-8
Formula:
C6H11NO2
Molecular Weight:
129.159
Pathway:
Neuroscience
Purity:
0.9813
SMILES:
NC1(CCCC1)C(O)=O
Target:
NMDAR

References

Gargiulo API, et, al. Effects of Cycloleucine in the Nucleus Accumbens Septi on the Elevated plus Maze Test in Rats. Neuropsychobiology. 2020;79(3):191-197. S Amor, et al. The effect of cycloleucine on SFV A7(74) infection in mice. Br J Exp Pathol. 1987 Apr;68(2):225-35. Caboche M, et, al. RNA methylation and control of eukaryotic RNA biosynthesis. Effects of cycloleucine, a specific inhibitor of methylation, on ribosomal RNA maturation. Eur J Biochem. 1977 Mar 15;74(1):19-29. Dimock K, et, al. Cycloleucine blocks 5'-terminal and internal methylations of avian sarcoma virus genome RNA. Biochemistry. 1978 Aug 22;17(17):3627-32.