TargetMol

(1 α,1'S,4β)-Lanabecestat

Product Code:
 
TAR-T10014
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10014-50mg50mg£655.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T10014-100mg100mg£1,066.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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Further Information

Bioactivity:
(1α,1'S,4β)-Lanabecestat is a Beta site APP Cleaving Enzymel (BACE1) inhibitor, and has IC50s of 2.2 nM (TR-FRET assay) and 0.28 nM (sAPPp release assay), respectively.
CAS:
1384082-96-5
Formula:
C26H28N4O
Molecular Weight:
412.537
Purity:
0.98
SMILES:
CO[C@H]1CC[C@]2(Cc3ccc(cc3[C@]22N=C(C)C(N)=N2)-c2cncc(c2)C#CC)CC1

References

1. Gabor Csjernyik, et al. Compounds and their use as bace inhibitors. WO2012087237A1.