TargetMol

Propantheline bromide

Product Code:
 
TAR-T1006
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1006-50mg50mg£99.00
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TAR-T1006-100mg100mg£111.00
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TAR-T1006-200mg200mg£125.00
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Further Information

Bioactivity:
Propantheline bromide competitively antagonizes acetylcholine activity mediated by muscarinic receptors at neuroeffector sites on smooth muscle and exocrine gland cells. Propantheline Bromide is the bromide salt form of propantheline, a quaternary ammonium compound structurally related to belladonna alkaloids. An aspartic acid residue present in the N-terminal portion of the third transmembrane helix of the muscarinic receptor is believed to form an ionic bond with the tertiary or quaternary nitrogen of the antagonist. Antagonism leads to a reduction of exocrine glands secretions and to relax the bronchial muscle and reduce tone and motility of intestinal smooth muscle.
CAS:
50-34-0
Formula:
C23H30BrNO3
Molecular Weight:
448.401
Pathway:
Neuroscience
Purity:
0.98
SMILES:
[Br-].CC(C)[N+](C)(CCOC(=O)C1c2ccccc2Oc2ccccc12)C(C)C
Target:
AChR

References

1. Saitoh H, et al. J Pharmacobiodyn. 1986 Dec; 9(12):1008-14.