TargetMol

6RK73

Product Code:
 
TAR-T10188
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10188-1mg1mg£189.00
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TAR-T10188-5mg5mg£322.00
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TAR-T10188-1mL1 mL * 10 mM (in DMSO)£348.00
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TAR-T10188-10mg10mg£502.00
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TAR-T10188-25mg25mg£768.00
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TAR-T10188-50mg50mg£1,026.00
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Quantity:
TAR-T10188-100mg100mg£1,348.00
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Quantity:
TAR-T10188-500mg500mg£2,657.00
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This product comes from: United States.
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Further Information

Bioactivity:
6RK73 is a covalent irreversible and specific UCHL1 inhibitor (IC50: 0.23 ?M). 6RK73 shows almost no inhibition of UCHL3 (IC50: 236 ?M).
CAS:
1895050-66-4
Formula:
C13H17N5O2S
Molecular Weight:
307.37
Purity:
1
SMILES:
N(C(=O)[C@@H]1CN(C#N)CC1)C=2SC(=CN2)N3CCOCC3

References

Liu S, et al. Deubiquitinase activity profiling identifies UCHL1 as a candidate oncoprotein that promotes TGF?-induced breast cancer metastasis. Clin Cancer Res. 2019 Dec 19. pii: clincanres.1373.2019.