TargetMol

Netarsudil mesylate

Product Code:
 
TAR-T10358L2
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10358L2-5mg5mg£1,171.00
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TAR-T10358L2-50mg50mg£2,303.00
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TAR-T10358L2-100mg100mg£3,042.00
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This product comes from: United States.
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Further Information

Bioactivity:
Netarsudil mesylate is an inhibitor of Rho-associated protein kinase (ROCK) and norepinephrine transporter (NET) with effective in intraocular pressure (IOP) reduction.
CAS:
1422144-42-0
Formula:
C30H35N3O9S2
Molecular Weight:
645.74
Purity:
0.98
SMILES:
CS(O)(=O)=O.CS(O)(=O)=O.Cc1ccc(C(=O)OCc2ccc(cc2)[C@@H](CN)C(=O)Nc2ccc3cnccc3c2)c(C)c1

References

1. Wang RF, et al. Effect of 0.04% AR-13324, a ROCK, and norepinephrine transporter inhibitor, on aqueous humor dynamics in normotensive monkey eyes. J Glaucoma. 2015 Jan;24(1):51-4. 2. Levy B, et al. Ocular hypotensive safety and systemic absorption of AR-13324 ophthalmic solution in normal volunteers. Am J Ophthalmol. 2015 May;159(5):980-5.e1.