TargetMol

TAK1/MAP4K2 inhibitor 1

Product Code:
 
TAR-T10444
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10444-5mg5mg£310.00
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TAR-T10444-50mg50mg£870.00
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TAR-T10444-100mg100mg£1,348.00
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This product comes from: United States.
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Further Information

Bioactivity:
TAK1/MAP4K2 inhibitor 1 is a potent dual inhibitor of TGFβ-activated kinase 1 (TAK1) and MAP4K2 (IC50s: 41.1 nM and 18.2 nM).
CAS:
1315330-11-0
Formula:
C29H31F3N6O2
Molecular Weight:
552.602
Purity:
0.98
SMILES:
CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(Oc4ncnc5[nH]c(C)cc45)c3)cc2C(F)(F)F)CC1

References

1. Tan L, et al. Discovery of type II inhibitors of TGF?-activated kinase 1 (TAK1) and mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2). J Med Chem. 2015 Jan 8;58(1):183-96.