TargetMol

CCR6 inhibitor 1

Product Code:
 
TAR-T10715
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10715-1mg1mg£189.00
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TAR-T10715-5mg5mg£369.00
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TAR-T10715-1mL1 mL * 10 mM (in DMSO)£402.00
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TAR-T10715-10mg10mg£517.00
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TAR-T10715-25mg25mg£790.00
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TAR-T10715-50mg50mg£1,050.00
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Quantity:
TAR-T10715-100mg100mg£1,396.00
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This product comes from: United States.
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Further Information

Bioactivity:
CCR6 inhibitor 1 is a potent and selective CCR6 inhibitor (IC50s: 0.45 and 6 nM for monkey and human CCR6), much more selective at CCR6 over human CCR1 (IC50, > 30000 nM), and CCR7 (IC50, 9400 nM).
CAS:
2437547-04-9
Formula:
C24H23F3N4O3S
Molecular Weight:
504.52
Pathway:
Microbiology/Virology|Immunology/Inflammation
Purity:
0.98
SMILES:
O=S([C@H](CC1)CC[C@@H]1NC2=NC=C(C(F)(F)F)C=C2)(C3=CC=C(C4=CC=NC(C(N)=O)=C4)C=C3)=O
Target:
CCR

References

1. Tawaraishi T, et al. Identification of a novel series of potent and selective CCR6 inhibitors as biological probes. Bioorg Med Chem Lett. 2018 Oct 1;28(18):3067-3072.