TargetMol

MMV008138

Product Code:
 
TAR-T12084
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12084-5mg5mg£370.00
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TAR-T12084-50mg50mg£1,564.00
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Quantity:
TAR-T12084-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
MMV008138 inhibits the growth of P. falciparum Dd2 strain (IC50 of 250 nM).
CAS:
1679333-73-3
Formula:
C18H14Cl2N2O2
Molecular Weight:
361.22
Purity:
0.98
SMILES:
OC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1)c1ccc(Cl)cc1Cl

References

1. Ghavami M, et al. Biological Studies and Target Engagement of the 2- C-Methyl-d-Erythritol 4-Phosphate Cytidylyltransferase (IspD)-Targeting Antimalarial Agent (1 R,3 S)-MMV008138 and Analogs. ACS Infect Dis. 2018 Apr 13;4(4):549-559. 2. Yao ZK, et al. Determination of the active stereoisomer of the MEP pathway-targeting antimalarial agent MMV008138, and initial structure-activity studies. Bioorg Med Chem Lett. 2015 Apr 1;25(7):1515-9.